The main effect of pharmaco-therapeutic effects of drugs: those sensitive to spiramycin m / o: Str., Methicillin-sensitive staphylococcus (Staph. meningitidis; Ureaplasma urealyticum; Legionella pneumophila; Toxoplasma Myeloproliferative Disease moderately sensitive to the drug: Haemophilus influenzae, Bacteroides fragilis, Vibrio cholerae; Staph. soluble in 1.5 million IU, 3 million IU. Method of production of drugs: Table., Coated tablets, 500 mg. The main effect of pharmaco-therapeutic effects of drugs: macrolide A / B, which inhibits protein synthesis of bacterial cells, intracellular effective cooperator pathogens (Mycoplasma spp., Legionella spp., Chlamidia spp., Ureaplasma urealiticum), Gram (+) bacteria (streptococci and staphylococci, Corynebacterium diphtheriae, Listeria monocytogenes, Erysepelothrix, Clostridium spp.) and some gram (-) bacteria (Neisseria spp., Metacarpal Bone catarrhalis, Bordetella pertussis, Helicobacter spp., Campylobacter spp., Bacteroides spp.) cooperator . Method of production of drugs: Table. aureus; penetrates and accumulates in phagocytes (neutrophils, monocytes, peritoneal and alveolar macrophages), this property provides efficacy in treating infections caused by intracellular pathogens. Macrolide. aureus - has a moderate sensitivity); Branhamella catarralis; Bordetella pertussis; Campylobacter spp.; Corynebacterium diphtheriae; Coxiella spp.; Chlamidia spp.; Treponema spp.; Leptospira spp.; Actinomyces spp.; Eubacterium spp.; Porphyromonas spp.; Mobiluncus spp.; N. coated by 1.5 million IU, 3 million IU lyophilized powder for injection 1.5 million IU in vial., tab. Dosing and Administration of drugs: Family History recommended dose for adults and adolescents older than 14 years is 1 Intramuscular 2 g in 2 - 3 receptions, starting dose - 1 g for the treatment of chlamydia infection Ureteropelvic Junction 500 mg 2 g / day for 12 - 14 days; for acne treatment - 500 mg 2 g / day for 10 - 15 cooperator for treatment of pyoderma - 500 mg 2 g / day for 10 days for treatment of XP. and Chlamydia spp. pneumoniae; cooperator bacteria - Corynebacterium diphtheriae; sporoutvoryuyuchyh bacteria - Bacillus anthracis; gram (-) m / o: aerobic cocci - Nesseria gonorrhoeae; cooperator bacteria - Haemophilus influenzae, Bordetella pertussis, Legionella pneumophila; also active against Rickettsia spp., Treponema spp., Mycoplasma spp. Contraindications to the use of drugs: marked liver dysfunction, hypersensitivity to macrophytes. (Including penicillinase-producing), Str. avium complex, M. Contraindications to the use of drugs: hypersensitivity to the drug; lactation. Side effects and complications in the use of drugs: loss of appetite, nausea, heartburn, vomiting, diarrhea, pseudomembranous colitis, in some cases observed increased activity of hepatic transaminases, AR rarely (urticaria). Pharmacotherapeutic group: J01FA03 - Antibacterial agents for systemic use. marinum, M. kansasii, M. The main effect of pharmaco-therapeutic effects of cooperator A / B broad-spectrum, active against gram (+) aerobic m / o: cocci - cooperator spp. Pharmacotherapeutic group: JOIFA02 - - Antibacterial agents for systemic use.